Clean & Clear Persa-Gel 10

Bottom Line

Clean & Clear Persa-Gel 10 contains the highest dosage of benzoyl peroxide (10 percent) allowed in an over-the-counter (OTC) acne treatment. It's recommended for those with occasional blemishes that are stubborn and resilient to other OTC treatments. Reviewers recommend applying the formula in very thin layers because the potent treatment can be quite drying. Experts recommend using maximum-strength formulas such as this one only after lower-dose formulas have failed to produce desired results. If you prefer an all-over acne treatment, La Roche-Posay Effaclar Duo (*Est. $40 for 1.35 oz.) is rated highly and our Best Reviewed pick.

Performance

Packs a punch. Experts recommend Clean & Clear Persa-Gel 10 for those with stubborn acne that resists other forms of treatment. It may be too strong for some, especially those with sensitive skin. Persa-Gel contains 10 percent benzoyl peroxide, the strongest dosage available in an over-the-counter treatment. Reviewers say it is very drying and often causes irritation, but most say the speedy results are worth it and that it's useful as a spot treatment. Several users say Persa-Gel clears up acne in as little as one to three days.

Feel and Smell

Fragrance-free formula absorbs into skin quickly. Persa-Gel is fragrance-free and has a lotion-like texture. One reviewer at MakeupAlley.com says, "Its very creamy and smooth consistency soaks into the skin quickly."