Clean & Clear Persa-Gel 10 contains the highest dosage of benzoyl peroxide (10 percent) allowed in an over-the-counter (OTC) acne treatment. It's recommended for those with occasional blemishes that are stubborn and resilient to other OTC treatments. Reviewers recommend applying the formula in very thin layers because the potent treatment can be quite drying. Experts recommend using maximum-strength formulas such as this one only after lower-dose formulas have failed to produce desired results. If you prefer an all-over acne treatment, La Roche-Posay Effaclar Duo (*Est. $40 for 1.35 oz.) is rated highly and our Best Reviewed pick.
Packs a punch. Experts recommend Clean & Clear Persa-Gel 10 for those with stubborn acne that resists other forms of treatment. It may be too strong for some, especially those with sensitive skin. Persa-Gel contains 10 percent benzoyl peroxide, the strongest dosage available in an over-the-counter treatment. Reviewers say it is very drying and often causes irritation, but most say the speedy results are worth it and that it's useful as a spot treatment. Several users say Persa-Gel clears up acne in as little as one to three days.
Fragrance-free formula absorbs into skin quickly. Persa-Gel is fragrance-free and has a lotion-like texture. One reviewer at MakeupAlley.com says, "Its very creamy and smooth consistency soaks into the skin quickly."
Review Credibility: Excellent Paula Begoun, who relies heavily on published studies in medical journals, gives Persa-Gel 10 her highest rating. Although it can be drying, she says it is an excellent option for stubborn cases of acne that won't respond to less-potent formulas.
Review: Persa-Gel 10, Maximum Strength, Paula Begoun, April 1, 2013
Review Credibility: Good Nearly 900 reviewers at MakeupAlley.com give Persa-Gel 10 a high overall rating of 4.1 out of 5 stars. Several say they see results in as little as one to three days, although many users complain that it dries out their skin.
Review: Clean & Clear Persa-Gel 10, Contributors to MakeupAlley.com, As of April 2013
Review Credibility: Good More than 450 reviewers at Acne.org give Clean & Clear Persa-Gel a high overall rating -- 4.12 out of 5 stars. Users praise the formula for quickly making a dramatic difference in the appearance of their skin. Some say it dries white and is best used at night.
Review: Clean & Clear - Persa-Gel 10, Maximum Strength, Contributors to Acne.org, As of April 2013
Review Credibility: Good Users at Drugstore.com praise Persa-Gel 10 for its affordable price tag and quick results. Some complain that it bleaches towels and clothing and leaves skin dry and irritated.
Review: Clean & Clear Persa-Gel 10, Maximum Strength, Contributors to Drugstore.com, As of April 2013