
Like most over-the-counter diet pills, Lean System 7 is not subject to Food and Drug Administration (FDA) approval. But unlike most nutritional supplements, Lean System 7 has been subjected to clinical testing that, while brief in duration and financed by the manufacturer, indicates Lean System 7 or its main ingredient (7-keto) may have some success in helping you lose a few pounds. These studies did not measure long-term effects or safety. Lean System 7 also contains herbal stimulants, including bitter orange, which many experts say has ephedra-like effects and is potentially dangerous. Some users also complain of jitters.
There aren't any professional reviewers who try to rate diet pills by effectiveness. Rather, we found articles and studies about the ingredients, along with synopses of clinical articles. We found two credible tests by the Minnesota Applied Research Center in reports published by the journals Nutrition and Current Therapeutic Research, one involving Lean System 7 and the other using a similar product containing 7-keto. ConsumerLabs.com doesn't test Lean System 7 on humans but does run it through lab tests to see if it contains what it claims to.

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Our Sources
This paper reports on a 2003 double-blind placebo study by the Minnesota Applied Research Center. The group taking Lean System 7 reduced hip circumference by nearly two centimeters more than the placebo group, but keep in mind that this study was paid for by the manufacturer.
Review: Effect of Lean System 7 on Metabolic Rate and Body Composition, J. Zenk, et al, Feb. 2005
2. Consumer Lab
ConsumerLab.com does extensive laboratory testing of health products. Lean System 7 is included in this report, which is a chemical analysis rather than testing on humans, but a subscription is required to see it.
Review: Product Review: Weight-loss Supplements, Editors of ConsumerLab.com
3. Current Therapeutic Research
This Minnesota Applied Research Center study looks at 7-keto, an ingredient in Lean System 7, although the article focuses on a product called 7-Keto Naturalean as compared to a placebo. The study says those taking the supplement, exercising and reducing calories lost more weight than those who simply reduced their calories and exercised.
Review: The Effect of 7-Keto Naturalean on Weight Loss: A Randomized, Double-blind, Placebo-controlled Trial, J. Zenk, et al, April 2002
Articles on this website are written by people in the fitness or nutrition industries and, while scientific, testing is hands-on. The recommendation is that Lean System 7 is "not a magic pill" that absolves one from exercise. The tester needed to reduce the dosage to eliminate jitters.
Review: Lean System 7 Review: Does Lean System 7 (LS7) Work?, Editors of UltimateFatBurner.com, Not Dated
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