Frontline Plus for Dogs
Frontline Plus for Dogs

Topical flea control treatment for dogs

*Est. $75 for a six-month supply
Estimated Price

Veterinarians and pet owners both recommend Frontline Plus for Dogs for wiping out a flea infestation. This topical medication contains two active ingredients: One kills adult fleas, ticks and chewing lice, while the other quickly prevents flea eggs and larvae from developing. This product is applied monthly to the skin between a dog's shoulder blades. It continues to work even after baths, swimming and exposure to rain. No prescription is needed to purchase Frontline Plus, which is safe for use on dogs that are at least 8 weeks old.

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Advantage II for Cats
Advantage II for Cats

Topical flea control treatment for cats

*Est. $60 for a six-month supply
Estimated Price

Advantage II for cats is a reformulated version of Advantage for Cats, a topical flea treatment that earns good ratings from vets. The new version contains two ingredients, one that kills adult fleas and one that prevents immature fleas from developing. However, unlike Frontline Plus, Advantage II doesn't kill ticks. Advantage II is applied once monthly to the back of the neck, and its effectiveness is not diminished by water exposure. You can purchase a four- to 12-month supply of Advantage online without a vet's prescription, but the cat should be at least 8 weeks old.

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Capstar for Dogs and Cats
Capstar for Dogs and Cats

Oral flea medication for dogs and cats

*Est. $30 for six doses
Estimated Price

Capstar is intended to quickly and safely knock down an existing flea problem, rather than prevent one from occurring. It starts working within 30 minutes of dosing, and it doesn't have the mess sometimes associated with topical treatments. Moreover, both vets and pet owners report fewer side effects with Capstar than with any other flea control product. Capstar, available in strengths for dogs over 25 pounds or for cats and smaller dogs, can be purchased online without a prescription. It is safe to use on puppies or kittens as young as 4 weeks old, as long as they weigh at least 2 pounds.

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See a side-by-side comparison of key features, product specs, and prices.

Flea Control Runners Up:

Frontline Plus for Cats *Est. $75 for a 6-month supply

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