Advantage II for Dogs is an updated version of Advantage for Dogs. It adds an ingredient to stop the development of flea eggs, while still killing adult fleas within 12 hours. It is effective against fleas and flea larvae for up to a month, but it can be reapplied after a week should fleas return. Advantage II for Dogs also works on chewing lice, but unlike its top competitor, Frontline Plus for Dogs (*Est. $75 for a six-month supply), it is not effective against ticks.
Advantage II is a liquid that is squeezed from a tube onto a dog's back -- between the shoulder blades for smaller dogs and at multiple points along the back for larger dogs. Although most users find it easy to apply, it does create more mess than oral products such as Capstar for Dogs and Cats (*Est. $30 for six doses). It also has more side effects than Capstar, most commonly skin irritation, but overall rates of side effects are still low. Although most users say they find this product effective, we saw multiple complaints that it didn't work at all or didn't remain effective for more than a week or so. Several dog owners complain that Advantage II is less effective on their dogs' fleas than the original version of Advantage.
Since it is relatively new, Advantage II for Dogs has not received much in the way of feedback from vets. Owners do weigh in at retail sites, however. We found more than 150 reviews of Advantage II for Dogs from dog owners at Petco.com. At 1800PetMeds.com, there are more than 1,800 reviews for Advantage II, but that includes feedback on Advantage II for Cats as well. The Veterinary Partner website has information about the ingredients in Advantage II. Though the information at sites like Dogster.com and Main Street Pet Care doesn't address the new ingredient added to kill flea larvae, the comments on the ingredients in the original version of Advantage -- and found in Advantage II as well -- can be helpful.
There are roughly 1,800 user reviews of Advantage II here, but they cover the versions for cats as well as the ones for dogs. Feedback is generally strong, and Advantage II earns 4.2 stars overall.
Review: Advantage II , Contributors to 1800PetMeds.com
Advantage II for Dogs receives more than 200 reviews from dog owners at Petco.com. Its overall rating is 4.5 stars out of 5, and 90 percent of users say they would recommend it. While most do owners find it effective, we did see complaints that it didn't work or lost its efficacy after about a week.
Review: Advantage II Once-A-Month Topical Flea Treatment for Dogs & Puppies, Contributors to Petco.com
Veterinarian Carol S. Foil addresses the various flea control products available. She notes that the original version of Advantage for Dogs killed fleas fast and remained effective for at least two weeks. Nylar, the ingredient added to Advantage II to kill flea larvae, is said to be very effective in destroying flea eggs.
Review: Flea Control, Carol S. Foil
4. Main Street Pet Care
In this article, the staff of Main Street Pet Care notes that the original Advantage can be helpful for pets with flea allergies because it acts very quickly. That said, oral flea products are recommended more highly.
Review: Flea and Tick Control, Staff of Main Street Pet Care
Dogster.com is an online resource for everything related to dogs. In this blog entry, veterinarian Eric Barchas discusses the safety of various flea control treatments. He says that the original Advantage is one of several flea remedies that rarely have side effects, and even when they occur, they are rarely severe.
Review: Vet Blog Discusses Safety and Efficacy of Flea Control Products, Eric Barchas, May 26, 2010