
Veterinarians -- the most reliable source of recommendations for flea-control products -- say Advantage Once-a-Month Topical Flea Treatment for Dogs & Puppies is overall the most effective external flea-control treatment. This ointment is applied once a month to the back of the dog's neck, kills all fleas within 12 hours, prevents reinfestations for four weeks and will still work after shampoos, baths or exposure to rain and sun. Some experts, however, prefer internal flea-control medications such as Sentinel Flavor Tabs (*est. $60 to $85 for six-pack, depending on dog's weight); this decision is best left up to your veterinarian.
The three most convincing recommendations for Advantage Once-a-Month Topical Flea Treatment for Dogs & Puppies are from an article on Helium.com in which 15 authors -- including veterinary professionals -- weigh in on the best anti-flea remedies, About.com's guide to cats, and that of veterinarian Larry Cohen of DrLarryPetVet.com. We supplement these reviews with owner posts on the retail site Petco.com.

| Advantage Topical Flea Treatment for Dogs 21-55 Lbs (6 Applications) | |
(199 reviews) In Stock. |
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Our Sources
1. Helium.com
In this series of 15 short articles, writers ranging from kids to veterinarians recommend the best anti-flea products. Advantage receives a lot of mentions here for all pets.
Review: The Best Products for Getting Rid of Fleas, Contributors to Helium.com
In this brief but helpful article, veterinarian Larry Cohen describes the pros and cons of three common topical anti-flea medications. He says Advantage is "very effective in killing fleas quickly" but has no effect on ticks. All three products receive equally high ratings, but Cohen says Advantage is the most effective against fleas.
Review: Flea and Tick Products, Larry Cohen
3. About.com
About.com cats guide Franny Syufy gives brief descriptions of the top three topical flea-control preparations: Advantage, Frontline and Revolution. She says she uses Advantage for her cats and kittens, and hasn't seen any fleas in years. It isn't clear if she's ever tried the others. (Note that About.com and ConsumerSearch share the same parent company but are not editorially affiliated.)
Review: Topical Flea Control Products for Cats, Franny Syufy
4. Petco.com
Among topical flea medications, Advantage and Frontline are the clear favorites here, receiving the most positive reviews from the highest number of users.
Review: Flea & Tick Control, Contributors to Petco.com
Flea Control Runners Up:
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3 picks including: About.com, Helium.com…
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2 picks including: PlacervilleVet.com, Main Street Pet Care…
2 picks by top review sites.
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