
First Response Early Result repeatedly tests as the most sensitive home pregnancy test on the market in scientific studies and consumer reviews. With the ability to detect concentrations of human chorionic gonadotropin (hCG) at concentrations as low as 6.3 mIU/ml, First Response is able to detect 95 percent of pregnancies in one study on the first day of the missed period. Both scientific studies and consumer testing also find the First Response Early Result to be one of the easiest nondigital pregnancy tests to interpret at low concentrations of hCG. Though the high sensitivity to hCG does allow a woman to test as early as six days before a missed period, as with all pregnancy tests, the First Response will be more accurate the later it is taken. Natural biological variances mean that as many as 10 percent of women will have yet to implant, and yet to produce hCG, on the first day of a missed period. Experts recommend you buy First Response Early Result in two-test kits, as testing again a week later will greatly increase the accuracy of the test. All home pregnancy tests, including this one, receive user complaints about false positives and false negatives, and some women find the colored lines of the First Response Early Result hard to interpret. Digital tests like the Clearblue Easy Digital Pregnancy Test (*Est. $18 for three-test kit) are more expensive and less sensitive but do clearly say pregnant or not pregnant.
We found the best comparisons and data on the sensitivity of First Response Early Result in various medical journals, including the Journal of the American Pharmacists Association, American Journal of Obstetrics and Gynecology, Clinical Chemistry and Current Medical Research and Opinion. A major consumer reporting group also offers independent testing to verify the sensitivities and readability of various home pregnancy tests. Parents.com and About.com offer rankings and recommendations while consumers at Viewpoints.com, Drugstore.com and Epinions.com discuss their personal experiences with pregnancy tests.

| First Response Early Result Pregnancy Test, 2 tests | |
(4 reviews) In Stock. |
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Our Sources
1. Journal of the American Pharmacists AssociationDetails/Subscribe
This clinical study takes previous testing of home pregnancy tests (HPTs) a step further by using urine samples with a mixture of human chorionic gonadotropin (hCG) designed to mimic that seen in the early weeks of pregnancy. First Response Early Result is the most sensitive, detecting 6.3 mIU/ml of the hCG mixture. Test readers also have the highest confidence in reading positive and negative test results of the First Response Early Result.
Review: Sensitivity of Over-the-Counter Pregnancy Tests: Comparison of Utility and Marketing Messages, Laurence A. Cole et al., Sept. 28, 2005
2. American Journal of Obstetrics and GynecologyDetails/Subscribe
This clinical study first evaluates the concentration of human chorionic gonadotropin (hCG) in the urine of 25 women achieving pregnancy at the time of their missed periods. The researchers then test 18 home pregnancy tests for sensitivity at various concentrations of hCG. First Response was consistently the most sensitive, able to detect 12.5 mIU/ml of hCG, and it would have caught 95 percent of pregnancies in this study on the first day of a woman's missed period.
Review: Accuracy of Home Pregnancy Tests at the Time of Missed Menses, Laurence A. Cole, Sarah A. Khanlian, Jaime M. Sutton, Suzy Davies, William F. Rayburn, Jan. 2004
This clinical study evaluates 592 urine samples from women at various stages in their pregnancies to determine what form of human chorionic gonadotropin (hCG) is prevalent at what time. Researchers also evaluate the sensitivity of 15 home pregnancy tests (HPTs) at various concentrations of both regular hCG and another form, hyperglycosylated hCG (H-hCG). They find that the hyperglycosylated form of hCG makes up more than half of the hCG in the urine of pregnant women in the first weeks of pregnancy. First Response is able to detect both forms of hCG at concentrations of 25 mIU/ml.
Review: Detection of Early Pregnancy Forms of Human Chorionic Gonadotropin by Home Pregnancy Test Devices, Stephen A. Butler, Sarah A. Khanlian and Laurence A. Cole, Dec. 2001
4. Current Medical Research and OpinionDetails/Subscribe
This clinical study funded by the manufacturer of the Clearblue Easy Digital Pregnancy Test compares that test with five other over-the-counter, nondigital pregnancy tests, including the First Response Early Result. The Clearblue Easy Digital Pregnancy Test is found to be the most sensitive and easily read test. First Response is found to detect 25 mIU/ml of hCG more than 65 percent of the time.
Review: Comparison of Accuracy and Certainty of Results of Six Home Pregnancy Tests Available Over-the-Counter, Catherine Tomlinson, Jayne Marshall and Jayne E. Ellis, May 2008
This article details the results of a major consumer group's testing of 18 home pregnancy tests (HPTs) done in 2003. First Response Early Result is named the most sensitive test, detecting 6.5 mIU/ml of hCG and earning an excellent rating for ease of interpretation of the results.
Review: The Best Pregnancy Tests, Tatiana Morales, Jan. 28, 2003
Shape includes a short, lay-person-friendly summary of the American Journal of Obstetrics and Gynecology study results, noting that First Response is the most sensitive home pregnancy test, detecting 95 percent of pregnancies on the first day of a missed period.
Review: The Most Accurate Early Pregnancy Tests, Sharon Cohen, May 2004
7. Parents.comDetails/Subscribe
Parents.com offers detailed descriptions of 10 home pregnancy tests, including how they work, when and how to use them, and their cost. Though no scientific studies are performed on the tests, Parents.com does choose First Response Early Result as "great for testing early."
Review: 10 Home Pregnancy Tests (and How to Use Them), Sasha Emmons
8. About.com
Robin Elise Weiss, About.com's guide to pregnancy and birth, tests six home pregnancy tests (HPTs) with a woman who is five weeks pregnant. First Response Early Result earns 5 stars for its ability to be used up to three days before your missed period, its ease of use, accuracy and good value. (Note: ConsumerSearch is owned by About.com, but the two don't share an editorial affiliation.)
Review: Top 7 Pregnancy Tests, Robin Elise Weiss
9. About.com
About.com offers information on home pregnancy tests (HPTs) under their Contraception guide. Included is detailed information about how HPTs work and the accuracy and sensitivity of early-detection HPTs. Dawn Stacey also provides a brief review of the results of the 2004 American Journal of Obstetrics and Gynecology scientific study on HPTs, which chose First Response Early Result as the most sensitive HPT. (Note: ConsumerSearch is owned by About.com, but the two don't share an editorial affiliation.)
Review: Home Pregnancy Tests, Dawn Stacey, Dec. 12, 2010
An offshoot of ParentingWeekly.com, PreconceptionWeekly.com offers tips and guides for women planning to conceive. This article includes a chart of 25 home pregnancy tests (HPTs) and their reported sensitivities to human chorionic gonadotropin (hCG). It also explains the results of the 2003 testing of a major consumer reporting group and the 2004 article from the American Journal of Obstetrics and Gynecology listed above. Both choose First Response Early Result as the most sensitive home pregnancy test.
Review: Which Home Pregnancy Tests Are Most Accurate?, Editors of PreconceptionWeekly.com
11. Fertility Plus
This review includes quantitative sensitivity information reported by manufacturers for a large number of home pregnancy tests. First Response Early Result is the most sensitive, able to detect 6.3 to 15 mIU/ml of hCG in urine.
Review: Home Pregnancy Test hCG Levels and FAQ, Editors of FertilityPlus.org
12. Viewpoints.com
This site offers not only consumer reviews but also summaries of those reviews and composite pros and cons lists for each home pregnancy test (HPT). First Response Early Result Pregnancy Test earns 4.35 stars out of a possible 5 with more than 70 reviewers. Reviewers like that the test can be used early, and most find the test accurate and reliable. However some reviewers complain that the test is too pricey, and there are reports of false negatives when testing early, though this may be due more to natural variability in the time of implantation than to faulty tests.
Review: First Response Early Result Pregnancy Test Reviews, Contributors to Viewpoints.com
13. Epinions.com
Epinions.com lists dozens of pregnancy tests, but only about 18 receive owner-written ratings. First Response Early Result is reviewed by more than 40 people and receives 3.5 out of 5 stars, with some women complaining the test doesn't work as early as advertised. This may be due more to variance in a woman's menstrual cycle than faulty tests. There are also some complaints that the results of the test are difficult to interpret.
Review: First Response Early Result Pregnancy Test, Contributors to Epinions.com
14. Drugstore.com
Drugstore.com, an online retailer, lists nearly a dozen home pregnancy tests (HPTs) on its website. First Response Early Result receives more than 100 reviews and has the highest rating, although that is only 3 out of 5 stars. There are a handful of complaints of false negatives with First Response when trying to use the test before a missed period.
Review: First Response Early Result Pregnancy Test Kit, Contributors to Drugstore.com
Pregnancy Tests Runners Up:
7 picks including: American Journal of Obstetrics and Gynecology, Drugstore.com…
3 picks including: Viewpoints.com…
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